CAIE A Level Biology 9700 · Biological molecules

Biological molecules: describe question

Describe4 marksStandard

The table below shows some features of two proteins, haemoglobin and collagen.

FeatureHaemoglobinCollagen
Solubility in waterSolubleInsoluble
Number of polypeptide chains4 (two α, two β)3 (each a long chain, about 1000 amino acids)
Overall shapeRoughly sphericalLong, rope-like fibres
Types of bonds stabilising structureHydrogen bonds, ionic bonds, hydrophobic interactions, disulfide bridges (in some regions)Hydrogen bonds, cross-links between chains (covalent bonds)
Presence of non-protein groupsYes – four haem groups, each with an iron ionNo
FunctionOxygen transport in bloodProvides tensile strength in tendons, skin, bones

Using the information in the table and your knowledge of protein structure, describe how the structures of haemoglobin and collagen relate to their different functions.

0 words · 4 marks

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How this question is marked

4 marks, so the mark scheme is looking for about 4 separate creditworthy points. Making the same point twice in different words earns it once.

Describe means: Say what happens or what something is like, in order and with detail. You are not being asked why. If there is data, quote it: name the trend, then give figures with units at the points where it changes.

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