A student treats actively dividing onion root tip cells with colchicine, a chemical that inhibits the polymerisation of tubulin into microtubules. When observed under a microscope, the treated cells show condensed chromosomes scattered throughout the cytoplasm, no visible spindle fibres, and the absence of a nuclear envelope. With reference to the stages of mitosis, explain why the cells have not progressed to metaphase and describe the normal behaviour of the spindle and nuclear envelope during the stages that occur prior to the observed block.
CAIE A Level Biology 9700 · The mitotic cell cycle
The mitotic cell cycle: explain question
Explain6 marksChallenge
How this question is marked
6 marks, so the mark scheme is looking for about 6 separate creditworthy points. Making the same point twice in different words earns it once.
Explain means: Give the reasons or the mechanism: why or how something happens. Link each point to the next with because, so or which means. A list of facts with no links usually loses the reasoning marks.
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