CAIE A Level Biology 9700 · Transport in mammals

Transport in mammals: explain question

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A researcher investigated carbon dioxide transport in human blood. Blood samples were taken from a volunteer at rest and immediately after 5 minutes of vigorous exercise. The concentration of chloride ions (Cl⁻) inside red blood cells (RBCs) and in plasma was measured. The results are shown in the table below.

Condition[Cl⁻] in RBCs (mmol dm⁻³)[Cl⁻] in plasma (mmol dm⁻³)
At rest70110
After exercise8595

Explain the mechanism of the chloride shift that accounts for the changes in Cl⁻ concentration observed after exercise, and discuss the importance of this process in carbon dioxide transport.

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