A patient with diabetes mellitus uses a blood glucose meter that employs test strips based on the enzyme glucose oxidase. The table below shows the colour change observed on the test strip for different glucose concentrations.
| Glucose concentration (mmol dm⁻³) | Colour observed |
|---|---|
| 0 | Light blue |
| 2 | Green |
| 4 | Yellow-green |
| 6 | Orange |
| 8 | Red-brown |
After consuming a carbohydrate-rich meal, the patient's blood glucose concentration rises.
Describe the principles of the glucose oxidase test strip and describe the negative feedback mechanisms that return blood glucose concentration to normal.