A biotechnology company is developing a diagnostic test for amoebic dysentery, caused by the protozoan Entamoeba histolytica. The test uses monoclonal antibodies that bind specifically to a surface protein antigen on the amoeba. Explain how monoclonal antibodies are produced using the hybridoma method and how they are used in this diagnostic test to detect the presence of the pathogen.
CAIE A Level Biology 9700 · Immunity
Immunity: explain question
Explain5 marksStandard
How this question is marked
5 marks, so the mark scheme is looking for about 5 separate creditworthy points. Making the same point twice in different words earns it once.
Explain means: Give the reasons or the mechanism: why or how something happens. Link each point to the next with because, so or which means. A list of facts with no links usually loses the reasoning marks.
More Immunity questions
- 5 marks · The table below shows the percentage of children vaccinated against a viral disease and the number of reported cases in two regions of a…
- 4 marks · A new vaccine has been developed against the rhinospike virus. It contains inactivated viral particles. Describe how this vaccine provides…
- 5 marks · The hybridoma method is used to produce monoclonal antibodies for use in diagnostic tests. Explain how monoclonal antibodies are produced…
- 4 marks · A person is infected with a pathogen for the first time. Describe the roles of macrophages, B-lymphocytes, T-helper cells and T-killer…
- 5 marks · A biotechnology company aims to produce a monoclonal antibody that can specifically detect a toxin produced by a pathogenic bacterium in…
- 4 marks · A student made the following statements about the four types of immunity: active natural, active artificial, passive natural, and passive…
Written by Markquill to follow the Cambridge International syllabus. Markquill is independent and is not affiliated with or endorsed by Cambridge International.