CAIE A Level Biology 9700 · Immunity
Malaria is caused by Plasmodium species. A researcher aims to develop a rapid diagnostic test that uses monoclonal antibodies to detect a Plasmodium antigen in blood samples from infected patients.
(a) Outline how the molecular structure of an antibody enables it to bind specifically to the Plasmodium antigen.
(b) Outline the hybridoma method used to produce the monoclonal antibodies for this test.
5 marks, so the mark scheme is looking for about 5 separate creditworthy points. Making the same point twice in different words earns it once.
Outline means: Give the main points briefly. Less detail than describe, but every key step has to be there. One short line per step, in order. The marks are for coverage, not depth.
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