Cellulase is an extracellular enzyme secreted by certain fungi. It catalyses the hydrolysis of cellulose to glucose. Two hypotheses used to describe enzyme action are the lock-and-key hypothesis and the induced-fit hypothesis.
Explain how the lock-and-key hypothesis and the induced-fit hypothesis differ in their description of the formation of the enzyme-substrate complex, and how each hypothesis relates to the lowering of activation energy.