CAIE A Level Biology 9700 · Immunity
Scientists have produced a monoclonal antibody that binds specifically to a surface antigen of the bacterium Haemophilus xyloosus, which causes a respiratory disease. Explain how this monoclonal antibody was produced using the hybridoma method and how its structure enables it to be used in a diagnostic test to detect the bacterium in patient samples.
5 marks, so the mark scheme is looking for about 5 separate creditworthy points. Making the same point twice in different words earns it once.
Explain means: Give the reasons or the mechanism: why or how something happens. Link each point to the next with because, so or which means. A list of facts with no links usually loses the reasoning marks.
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